History Tramadol

Tramadol is an old German analgesic, first marketed in 1977, but not sold in the U.S. until 1995. Crestor has not been assigned to kontoliruemym drugs, although he has many qualities of such drugs, like morphine and codeine. After only one year after admission to the market in the United States had received reports of serious side effects of this drug, even after receiving a single dose, including epileptornye seizures, dependence, and severe allergic reactions.
During the first year sales FDA received 83 reports of epileptornyh seizures and convulsions in patients who used tramadol. During the second year of sale FDA has received more than 200 reports of convulsions. Many of these messages indicate the origin of seizures in one day from the date of admission. Most of these people were healthy, aged 20 to 39 years, and most had not previously experienced a seizure. This adverse reaction can also occur when the recommended doses, but an overdose may increase the risk of seizures. Application of tramadol with antidepressants, including new selective inhibitors of neuronal capture and older tricyclic antidepressants, increases the risk of seizures. By careful evaluation of FDA to every message on the occurrence of adverse reaction to the drug accounted for 10 cases, which are not reported.
Tramadol has actions similar to the actions of narcotic analgesics such as morphine and codeine, including the likelihood of addiction, but he was not assigned to controlled drugs in approving the application. Manufactured drug company Ortho-McNeil Pharmaceutical, Raritan NJ strenuously urged doctors that abuse of tramadol is unlikely. During the first year after release to the market FDA received 115 reports of drug abuse, the development of dependence, the development of withdrawal or intentional overdose, associated with the use of Tramadol. The multitude of consumers who are not informed about the possibility of addiction to tramadol, could develop drug dependence.
Crestor is no more and sometimes less effective than combinations of codeine with aspirin or paracetamol. It is more dangerous, less effective and more expensive than other similar painkillers, and the FDA should take immediate steps to start the procedures for the removal of tramadol from the market.