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piątek, 20 maja 2011

Take Away The Pain With Tramadol

We can experience pain as a result of a variety of situations. Maybe you can not get through the day as a consequence of suffering pain after a car accident, or maybe your arthritis is causing unbearable pain. Whatever the reason, probably their pain can be eased with Tramadol, which is used to relieve pain that is moderate to moderately severe. End your pain with tramadol!

A trick Terrific

Tramadol is one of a group of medicines known as opioid agonists, which are similar to narcotics. Tramadol is a prescription drug, and can be found under the names Ultram and Ultram ER. The drug works by altering the way the body senses pain.

Use as prescribed

Taking tramadol for pain relief is simple – simply follow your doctor’s instructions. Normally, tramadol is taken every 4-6 hours as needed and can be taken with or without food. Tramadol comes only in tablet form.

In order to alleviate their pain with tramadol, it is vital to take the tablets as directed. Instead of being chewed, crushed, or split, tramadol tablets should be swallowed whole. Tramadol inhalation or injection can cause death.

A Daily Dose

Relief of pain depends on a daily dose of tramadol. Your doctor will prescribe a dose of tramadol that suits their circumstances. Usually, your doctor will start the medication over a period of low doses of the drug, and gradually increase the dose.

Regardless of the dose, it is vital to follow your doctor’s instructions when taking Tramadol. Taking a higher dose is taken more frequently, or take a longer period of time could lead to serious side effects or even death. Also, if you want to stop taking tramadol, you should consult your doctor before gradually reducing the dose.

Around the clock Pain Relief

Need pain relief over 24 hours a day? Therefore, manufacturers of tramadol has a solution for you! Tramadol extended release tablets are intended to relieve the pain started several hours after the tablets are digested first. These tablets are ideal for people who need pain relief during the night.

Not only


Tramadol is an brilliant choice for pain relief in a variety of situations. But, to be sure, is very vital to consult your doctor at each step of the road. Only under the direction of his doctor – in the selection of the dose and schedule that are right for you – you will be able to live a safe and pain free life.

Resources For Tramadol Users To Get Prescription Medication

Tramadol is a successful drug used to treat mild to severe pain. It functions much like codeine or morphine would. In comparison to morphine, it is around one tenth as potent. It also has less to no dependency risks- making Tramadol a wise choice in pain medication. But where can Tramadol users get the drug, exactly?


Getting Tramadol The Ancient-Fashioned Way


If you haven’t been blessed with Internet access (and our condolences if you aren’t), you are more than likely going to be making a visit to the pharmacist. This will require fuel to drive there, extra costs that go to pharmacy services, and of course the inconvenience of leaving one’s own home is present.


But the ancient-fashioned way isn’t the only option, even if one doesn’t have Internet access. Tramadol users can go online in public libraries to get recurring prescriptions and deliveries of the drug straight to their doorstep via FedEx Next Day. And if Internet access is available at your home- you don’t even have to leave the house!


How To Get Tramadol Online


Tramadol requires a prescription, which means a doctor’s approval is needed. Tramadol users have two choices: visit a real doctor to get the prescription and use it to get Tramadol online, or conference with an online pharmacist to get the prescription.


If a Tramadol user wishes to conference with an online pharmacist, all that is needed is an email account or even a telephone. This allows the pharmacist to question relevant questions to make sure there will be no complications or unnecessary risks involved with taking Tramadol.


In a sense, online users are getting a Free Prescription. They do not have to pay a doctor for the actual physical and checkup that doctors perform. Instead, a simple phone call or online chat can cut the costs completely. This Free Prescription is a fantastic benefit to those who aren’t too keen on spending more money than they have to.


Special Scenarios For Offline Tramadol Users


If you don’t have the Internet access needed for online pharmacies, there are still options to get the necessary prescription. As stated before, using a public library will allow a recurring billing and shipment to be enabled. The pharmacist can then call a cell phone or home phone at a certain time and date to make sure the prescription will go through.


Although many online pharmacies push email as the number one means of communication because of its lack of cost, most do offer the telephone conferencing option. This simplifies the process even more for Tramadol users, since return visits to the public library will be unnecessary. All that will be needed is a telephone and the number to the online pharmacy.


Final Thoughts On Resources For Tramadol Users


If you;re comfortable with spending unnecessary money on fuel, services, and fees- the ancient fashioned way may suit you. But for the technology savvy and thrifty individuals, which accounts for most of the population, online pharmacies are quick becoming a new precedent in prescription medication.


It is strongly recommended that Tramadol users take advantage of online pharmacies. As time goes on, the online pharmacy will eventually take over most of the pharmaceutical market. This will be a fantastic gift to consumers who will delight in the cheaper prices, convenience, and reliability that online pharmacies provide.

How Does Tramadol Suppress Pain?

Tramadol is an innovative and atypical analgesic. It is a centrally effective drug which is used for treating moderate to acute pain. Tramadol is a synthetic agent, 4-phenyl-piperidine analogue of codeine. It has actions on the GABAergic, noradrenergic and serotonergic systems. This drug was made by a German pharmaceutical company and was marketed under the name of Tramal. Later on this drug was licensed to many other companies across the world who markets it under various names. This drug is generally sold or marketed under the name hydrochloride salt or tramadol hydrochloride. Tramadol is available in an injection and oral medication formulations. Tramadol is not a controlled drug in most countries and can be easily bought by normal prescription.
Pain can be traumatizing at times. Burning or shooting sensations are regular pain forms but there are also neuropathic pains which can be worse and is caused due to diseases of the peripheral nervous system. Tramadol is considered to be a unique drug which kills pain but has mild opiate properties. It is generally considered that between 100gms to 400gms of Tramadol can effectively cure pain and provide immediate relief. But slight side effects may be experienced in extreme cases like nausea, sedation and dry mouth. But these side effects, if they occur, are very small lived. Once the treatment and medicine is stopped these side effects fade away too.
Tramadol works through modulation of the GABAergic, noradrenergic and serotonergic systems. It also has mild agonism of the µ-opioid receptor. Non-opioid activity contributes by showing the analgesic effects of tramadol. But this cannot be really antagonised by the µ-opioid receptor antagonist naloxone. Tramadol has serotonergic modulating properties which mean that it has the capacity to interact with other serotonergic agents. But the risk factor increases when tramadol is taken in combination with serotonin reuptake inhibitors. It may result in serotonin syndrome. This happens because agents potentate the effect of 5-HT in addition to inhibiting tramadol metabolism. These antagonist effects make Tramadol a potential applicant for people in neuropathic pain states.
What all of that means is that Tramadol is basically a pain revliever. It works by simply affecting the chemicals and receptors in the body which are associated with pain. Therefore the pain in the body is reduced. It can treat moderate to moderately severe pain.
Tramadol can also be used for other purposes, since tramadol has nonopioid analgesic it can be used for recreational purposes also. Through agonism of appropiate receptors Tramadol produce affects similar opioids. The effect is not nearly as intense because it has much lower affinity for the receptor.
Tramadol can be taken in several doses as prescribed by the doctor. The number of doses are given according to the pain. It is advisable not to drive after taking this medicine as slight dizziness or drowsiness may be caused due to intake of the drug. Alcohol should be avoided while taking tramadol as it can cause a perilous decrease in breathing and may lead to liver problems also.

niedziela, 15 maja 2011

10 Things You Should Know About Tramadol

Tramadol, the generic version of Ultram, is a synthetic analgesic medication. The exact mode of action of tramadol is unknown but it is said to work like morphine. Tramadol binds to opioid receptors in the brain -- receptors that transmit the sensation of pain throughout the body. Here are 10 things you should know about tramadol to ensure its safe use.
1 - Tramadol is prescribed to treat moderate to moderately severe pain.

Tramadol belongs to the class of drugs known as opiate agonists. Primarily, tramadol works by changing the way the body senses pain. Some people mistakenly believe that tramadol is an NSAID (nonsteroidal anti-inflammatory drug), but it is not.
2 - Tramadol is available in immediate release and extended release formulations.

Tramadol may be prescribed as an immediate release tablet (50 mg.) or as an extended release tablet (100, 200, or 300 mg.). The extended release tablets are usually reserved for patients with chronic pain who require continuous, long-term treatment. Your doctor will determine the appropriate dosage schedule for you.
3 - Tramadol extended release tablets must be taken whole, not split, chewed or crushed.

It is important to take tramadol properly and to follow prescribing instructions. If taken improperly or in a way that is not recommended, serious side effects and even death can result.
4 - Tramadol can be habit-forming for some people.

Do not take more tramadol than has been prescribed for you. Taking more tramadol or taking it more often can cause dependency on it. You should also not stop taking tramadol without first consulting your doctor. You may experience withdrawal symptoms if you stopped it suddenly. You doctor will likely decrease your dose of tramadol gradually.
5 - Drug interactions are possible with tramadol.

Be aware of the following possible drug interactions:

Carbamazepine reduces the effect of tramadol
Quinidine increases the concentration of tramadol by 50% to 60%
Combining tramadol with an MAO (monoamine oxidase inhibitor) inhibitor or SSRI (selective serotonin reuptake inhibitors) can lead to seizures or other serious side effects.


Be sure to tell your doctor about all medications you are taking.
6 - Tramadol, when combined with certain other substances, can increase central nervous system and respiratory depression.

In other words, breathing may be affected or even stop if tramadol is combined with alcohol, narcotic drugs, anesthetics, tranquilizers, or sedatives.
7 - The use of tramadol during pregnancy should be avoided.

Because the safety of tramadol use during pregnancy has not been established, the medication should not be used during pregnancy. The safe use of tramadol in nursing mothers has also not been established.
8 - Tramadol is usually well-tolerated. Any side effects are usually temporary.

Some of the common side effects associated with tramadol include:

nausea
constipation
dizziness
headache
drowsiness
vomiting

Less common side effects include: itching, sweating, diarrhea, rash, dry mouth, and vertigo. There have been patients who developed seizures after taking tramadol.
9 - A Cochrane Review of tramadol to treat osteoarthritis revealed some small benefit.

The Cochrane Review stated that when tramadol is taken for up to 3 months, there may be decreased pain, improvements in function and stiffness and overall well-being. However, tramadol can cause side effects that are significant enough to require that the patient must stop taking the medication. Risks outweigh benefits for many people who have tried tramadol.

10 - If an overdose of tramadol has occurred, call your local poison control center, or call 911 if it appears to be an emergency situation.

Symptoms of an overdose include decreased pupil size, difficulty breathing or staying awake, unconscious, coma, heart attack, or seizure. Call for help, even if you are unsure about what to do.



Tramadol PharmaReviewer

Tramadol indeed (as they say the media) has become a threat to public safety in Ukraine.

Tramadol indeed (as they say the media) has become a threat to public safety in Ukraine. It develops tramadol addiction to me with the same intensity as the acetylated opium ( “shirk”), and heroin, and some aspects of tramadolnoy curves have even more opastny shade than the dependence on acetylated opium. Tramadol destructive effect on the gastrointestinal tract and liver (when receiving oral), and strongly depresses the central nervous system.

History Tramadol

Tramadol is an old German analgesic, first marketed in 1977, but not sold in the U.S. until 1995. Crestor has not been assigned to kontoliruemym drugs, although he has many qualities of such drugs, like morphine and codeine. After only one year after admission to the market in the United States had received reports of serious side effects of this drug, even after receiving a single dose, including epileptornye seizures, dependence, and severe allergic reactions.
During the first year sales FDA received 83 reports of epileptornyh seizures and convulsions in patients who used tramadol. During the second year of sale FDA has received more than 200 reports of convulsions. Many of these messages indicate the origin of seizures in one day from the date of admission. Most of these people were healthy, aged 20 to 39 years, and most had not previously experienced a seizure. This adverse reaction can also occur when the recommended doses, but an overdose may increase the risk of seizures. Application of tramadol with antidepressants, including new selective inhibitors of neuronal capture and older tricyclic antidepressants, increases the risk of seizures. By careful evaluation of FDA to every message on the occurrence of adverse reaction to the drug accounted for 10 cases, which are not reported.
Tramadol has actions similar to the actions of narcotic analgesics such as morphine and codeine, including the likelihood of addiction, but he was not assigned to controlled drugs in approving the application. Manufactured drug company Ortho-McNeil Pharmaceutical, Raritan NJ strenuously urged doctors that abuse of tramadol is unlikely. During the first year after release to the market FDA received 115 reports of drug abuse, the development of dependence, the development of withdrawal or intentional overdose, associated with the use of Tramadol. The multitude of consumers who are not informed about the possibility of addiction to tramadol, could develop drug dependence.
Crestor is no more and sometimes less effective than combinations of codeine with aspirin or paracetamol. It is more dangerous, less effective and more expensive than other similar painkillers, and the FDA should take immediate steps to start the procedures for the removal of tramadol from the market.